Mononucleosis, often caused by the Epstein-Barr virus (EBV), has several virulence factors that contribute to its pathogenesis. Key factors include the virus's ability to evade the immune response through latent infection and the production of proteins that manipulate host cell signaling pathways. Additionally, EBV can induce polyclonal B-cell proliferation, leading to the characteristic symptoms of the disease. These factors collectively facilitate the virus's persistence in the host and contribute to the clinical manifestations of mononucleosis.
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