How does plasmodium make you sick?

Plasmodium, the parasite responsible for malaria, infects red blood cells after being transmitted to humans through the bite of infected Anopheles mosquitoes. Once inside the bloodstream, the parasite multiplies within the red blood cells, leading to their destruction and causing symptoms such as fever, chills, and anemia. The release of toxins during the parasite's life cycle triggers an inflammatory response, further contributing to the illness. Severe cases can lead to complications like organ failure and death if not treated promptly.