I also have a 2000 E320 and mine had the same problem. I thought at first that it was an integrated chip that went bad but found out through a Mercedes mechanic that's it's actually caused by a bad ribbon cable inside the speedometer cluster. Had I known that ahead of time I would have sent it off to be repaired and not changed it.
good taime
that's hapend with me today and i go to Mercedes servise and he fixsed aprblem thrw Mercedes computer company
best regards
maikel
amman Jordan
mop.00962788202029
you can find the answers in utube by type in "remove cluster in Mercedes-Benz"
sak jinowat
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