The best driving route from Asheville, NC, to Lake George, NY, typically involves taking I-26 East to I-40 East, then merging onto I-81 North. From I-81, you'll connect to I-84 East and finally take I-87 North to reach Lake George. This route covers approximately 600 miles and offers a mix of scenic views and major highways for a smooth drive. Always check for traffic updates and road conditions before you set out.
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