As of my last update, the NFL has featured several sets of brothers who have played in the league, but the exact number can change with new seasons and retirements. Some notable pairs include the Mannings (Peyton and Eli), the Boses (Nick and Joey), the Watts (J.J. and T.J.), and the Griffins (Shaquill and Shaquem). While there may not be a definitive list of 28 active brother pairs at any given time, the league has a rich history of sibling rivalries and collaborations. For the most accurate and current information, checking the latest NFL rosters would be necessary.
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