Monoclonal can be specific for several antigenic determinants?

Monoclonal antibodies are typically designed to target a single antigenic determinant, which allows for high specificity in binding to that particular epitope. However, some monoclonal antibodies can exhibit cross-reactivity, recognizing multiple related epitopes or antigens due to structural similarities. This can be advantageous in certain therapeutic or diagnostic contexts but may also lead to unintended interactions. Overall, while monoclonal antibodies are primarily specific, their reactivity can occasionally extend to several antigenic determinants.