How many baby squirrels can a mother squirrel have in a litter?

A mother squirrel typically has a litter size ranging from 2 to 8 baby squirrels, depending on the species and environmental conditions. Eastern gray squirrels, for example, usually have about 3 to 5 young per litter. Breeding generally occurs twice a year, in late winter and mid-summer, allowing for multiple litters annually.