Does Advil lower your heart rate?

Non-steroidal anti-inflammatories (NSAI's) will, in fact, increase your heart rate and blood pressure. Not by much, but prolonged use and overdosage can become dangerous, especially in people with existing heart problems. If it has a bad reaction with another drug or you're allergic to it, that could lower your heart rate by quite a lot (and cause jaundice, nausea, and a host of other symptoms); but that would be an indication to seek urgent medical attention.