What is the best huge lift Camshaft for a Chevy 350?

It depends on a couple of things.

Do you want hydrualic solid flat tappet( cheapest), hyd./solid roller ( more expensive, but high lift).

Vehicle weight.

Where do you want the power? off idle 4500prms or 3000-6500rpms? What's the redline?

Manual or automatic, rear gear ratio.

Street/strip or cruiser

Fuel economy (wider lsa), power or sound( tighter lsa)

Power brakes? Requires 18+" of vacuum to operate properly, 16+ with vacuum canister.

What heads/intake/compression,EFI or carburator,etc. (stock stuff max out before .500" of lift). EFI will need 112-116lsa vs. 110 usually for carb.

256-262 adv duration (210-218 @ .050 lift) 110 lsa for daily driver 1000-5600rpm 264-270 duration with 112lsa for up to 6500rpm, anything large will need a 114lsa <280 for 7000rpm redline.

Comp cams has xtreme energy cams design for fast/high lift

Their XE262h-10 has a rumbling idle, good power 1300-5600rpm .462/.469 lift with 1.5 rocker arms,still will work with power brakes, 9.25compression, 348hp/415 lb-ft

they can give you a recommendation by filling out a form that describes what you want.

- (@.050) - (302-350)

210-225 for stock equipment daily driver

215-230 dual plane, ported or aftermarket heads, 9.5-10.5cr, headers (street/strip)

220-240 single plane manifold, 10.5+cr

The old general rule was 230 degrees @ .050 lift was the recommended max for street use. I would personally "limit street cam" it to <220* for 302-327, <230* for 350-360, <240* for 383-408cuin.

I would go solid roller with cams bigger than 220* @ .050 due to hyd rollers are usually limited to 6200-6500rpm, unless building a stroker engine. Higher ratio Roller rockers can give you more lift while keeping a short duration for better idle/vacuum/low end power.