During the follicular phase of the ovarian cycle, estrogen stimulates the growth and thickening of the uterine lining (endometrium). This hormone promotes the proliferation of endometrial cells and increases blood flow to the area, preparing the uterus for a potential implantation of a fertilized egg. The rise in estrogen levels also enhances the secretion of other growth factors that support the development of the endometrium. Overall, this prepares the uterus for a possible pregnancy.
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