To remove the ECU from a 1999 Lexus LS400, first disconnect the negative battery terminal to ensure safety. Then, locate the ECU, which is typically found under the passenger side dashboard. Remove any screws or bolts securing the ECU, disconnect the wiring harness by pressing the release tab, and gently pull the ECU out from its mounting. Be cautious not to damage any connectors or wiring during the process.
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