When are crystals deposited in the joints?

Crystals are deposited in the joints primarily during conditions like gout and pseudogout. In gout, monosodium urate crystals form due to elevated levels of uric acid, leading to inflammation and pain. Pseudogout involves the deposition of calcium pyrophosphate dihydrate crystals, which can also cause joint swelling and discomfort. These deposits often occur during periods of metabolic imbalance or joint trauma.