How were Native Americans at disadvantage in their conflict with white settlers?

Native Americans were at a disadvantage in their conflicts with white settlers due to several factors, including significant disparities in technology and military tactics, as settlers often had access to advanced weaponry and organized military forces. Additionally, the settlers' numbers grew rapidly, overwhelming Native populations who were already dealing with the impacts of disease brought by Europeans. Furthermore, many Native American tribes were divided and lacked unified leadership, making coordinated resistance against the settlers challenging. Lastly, settlers often employed strategies such as broken treaties and manipulation to further their expansion, undermining Native American sovereignty and rights.