An IV cannula should be changed out if there are signs of infection, such as redness, swelling, or discharge at the insertion site. It should also be replaced if there is a change in the patency of the line, such as difficulty flushing or blood return. Additionally, routine changes are often recommended every 72 to 96 hours, depending on the facility's protocol and the type of cannula used. Regular assessment and adherence to best practices are essential to minimize complications.
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