Yes. A normally pleasant sour or bitter food can taste unpleasantly sour or bitter if taken after a mouthful of very sweet food. For example, an Apple might taste sour if bitten into after one eats a piece of very sweet candy.
The practice of "cleansing the palate" developed for this reason. Sometimes a small dish of tangy sherbet is served between the courses of a large meal, or a starchy cracker is eaten between sips of different wines.
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