When a fertilized egg has defective autosomes what is the usual result?

When a fertilized egg has defective autosomes, it often leads to developmental abnormalities or pregnancy loss. Such defects can result in conditions like Down syndrome or other genetic disorders, depending on the specific autosomes involved. In many cases, these abnormalities can cause the embryo to fail to develop properly, leading to miscarriage early in the pregnancy. Overall, the presence of defective autosomes significantly impacts the viability and health of the developing fetus.