Sprains should be iced as soon as possible after the injury occurs, typically for 15-20 minutes every 1-2 hours during the first 48 hours. This helps reduce swelling and pain. It's important to wrap ice in a cloth to protect the skin from frostbite and to take breaks between icing sessions. After the initial 48 hours, alternating between ice and heat may be beneficial, depending on the healing process.
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