Pharmacological action is the therapeutic action of the drug on the body. For example, how the drug acts on the cells, what the drug does to the cells. Whereas the alteration or changes produced after the drug has acted (the action being; how the drug acted and what action did the drug do) on the cells is pharmacologial effect. Simply, in layman's terms pharmacological action is what action the drug can do and the pharmacological effect is what the action of the drug has done.
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