How do you get the tetrodotoxin of a pufferfish?

Tetrodotoxin is a potent neurotoxin found primarily in certain species of pufferfish. To obtain it, pufferfish must be carefully harvested, as the toxin is concentrated in their organs, particularly the liver, ovaries, and skin. It is crucial to handle the fish with extreme caution and to follow strict safety protocols, as even small amounts of tetrodotoxin can be lethal. However, extracting and using tetrodotoxin is highly regulated and illegal in many regions due to its toxicity.