Can you flush Vyvanse out of your system with water?

Drinking water may help to some extent with the elimination of Vyvanse (lisdexamfetamine) from your system, as hydration can support kidney function and promote urination. However, Vyvanse is primarily metabolized by the liver and has a half-life of about 10 to 13 hours, meaning it will take time for the drug to be fully eliminated. There is no quick way to "flush" it out completely, and attempting to do so can be ineffective and potentially harmful. It's best to consult a healthcare professional for advice regarding medication management.