What does high levels of succinate dehydrogenase mean?

High levels of succinate dehydrogenase (SDH) can indicate increased mitochondrial activity and enhanced oxidative metabolism, as SDH is a key enzyme in the citric acid cycle and electron transport chain. Elevated SDH levels may also suggest increased cellular energy demands or a response to certain physiological or pathological conditions, such as hypoxia or tumor metabolism. In clinical contexts, high SDH levels can be associated with specific types of tumors, particularly in certain cancers, where they may serve as biomarkers for diagnosis or prognosis.