A female teddy bear dog, which is a crossbreed typically between a Shih Tzu and a Bichon Frise, can have an average litter size of 2 to 6 puppies. However, the exact number can vary based on factors such as the dog's health, age, and genetics. It's important to provide proper care and attention during pregnancy and whelping for the health of both the mother and her puppies.
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