How long after frostbite for gangrene to set in?

Gangrene can develop after frostbite if the affected tissue loses its blood supply and becomes necrotic. This process can occur within a few days to weeks after the initial frostbite injury, depending on the severity of the frostbite and individual factors such as overall health and circulation. Prompt medical treatment is crucial to minimize the risk of gangrene following frostbite.