Hydrocodone is what is called a pure mu receptor agonist. This refers to certain morphine receptors in the brain. Darvocet is a partiaial agonist/antagonist, which means it can compete against many common narcotic analgesics. It is not advisable to combine the two as the darvocet can cause withdrawal symptoms inthose individuals habituated to pure mu agonists. In addition, darvocet has harmful metabolites that can cause serious side effects including siezures, with repeated administration. In my opinion, darvocet, darvon, and Demerol, are only suitable for pain relief for the short term. Their toxicity is such that the FDA is currently considering their removal from the market.
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