Can you take excedrin migraine and dayquil same day?

This depends how much Excedrin Migraine or how much Dayquil you are having.

Both Excedrin (Extra Strength or Migraine) and Dayquil contain acetaminophen (Tylenol). An overdose of acetaminophen can cause liver damage, sometimes liver failure. You should not be taking more than 1000mg of acetaminophen in a six hour period of time, and no more than 4000mg in a 24 hour period.

Each tablet of Excedrin Extra Strength or Excedrin Migraine contains 250mg of acetaminophen. So, each dose contains 500mg.

Each tablet of Dayquil contains 325mg of acetaminophen. Each dose contains 650mg.

It is up to you to add up what you are taking so that you are not taking more than is recommended.

If you think you may have overdosed on acetaminophen, seek emergency care. The sooner they are able to treat you, the more likely it is they can help save your liver.