What is the biggest problem of White-Box testing either Static or Dynamic?

The biggest problem with White-Box testing, whether static or dynamic, is its complexity and the potential for overlooking untested paths or conditions within the code. This testing method requires a deep understanding of the internal workings of the application, which can lead to human error or biases in test design. Additionally, maintaining comprehensive test coverage can be challenging, especially as codebases evolve, resulting in missed defects or vulnerabilities.