How many skin cells do you shed in one hour?

The human skin cell shedding rate (called the desquamation rate) depends on factors such as the location of the skin being considered, the total area being considered, and the person's age. Even keeping the skin location, skin area, and age constant will result in different rates for different individuals.

The basic data for making approximate calculations can be found at http://www.nature.com/jid/journal/v74/n1/abs/5616091a.html

and Table 2 in particular.

As an example, if we take the average rate of all subjects and all sample areas given in the Table 2 referenced above, we obtain an average rate of 945 cells per square centimeter per hour. Let's assume 945 cells per square centimeter per hour is close to the average desquamation rate for the entire body even though it depends on location and the table gives actual rates that vary from a low of 530 to a high of 1856. There are 10,000 square centimeters in a square meter. Average adult humans have a skin area of somewhere between 1.5 and 2.0 square meters. This means the average human has somewhere between 15,000 and 20,000 square centimeters of skin. Multiplying this area by the average of 945 cells per square centimeter per hour gives us

14,175,000 to 18,900,000 cells per hour or

236,250 to 315,000 cells per minute