Can guppies and a female beta live together in a small tank?

Provided the tank is not too small. Remember the basic rules. :- 1 inch of fish needs a minimum of 1 gallon of water. :- Every tank needs a permanently running cycled filter. :- Every tank needs at least 50% of its water changed every week. Keep the above rules and your fish stand a chance. Fail in any of them and I can guarantee that you will have constant health problems with your fish.