How often do you change 3 oxygen sensors on Toyota Highlander 06?

On a 2006 Toyota Highlander, oxygen sensors should typically be replaced every 60,000 to 100,000 miles, depending on driving conditions and maintenance practices. If the check engine light indicates an issue or if you're experiencing poor fuel efficiency or emissions problems, it may be time to change them sooner. Regular inspections can help determine their condition and whether they need replacing. Always refer to the vehicle’s service manual for specific recommendations.