What is redistribution of drug?

redistribution is the process of reversible movement of drug from site of tissue to systemic circulation. many lipid soluble drug show this phenomenon as a result of termination of action of drug more rapidly if the site of action of drug is highly perfused organ. highly lipid solluble drug is moved early in highly perfused organ such as- brain,kidney,liver and heart follwed by partial perfused organ such as adipose tissue. if site of action is highly perfused organ in that condition action of drug somewhat terminate because drug become more rapidly move from highly perfused organ to blood by crossing the tissue memb. while max. of them accumulate in fatty tissue.