Can promethazine cause euphoria in higher doses?

Yes, promethazine can cause euphoria in higher doses, as it is an antihistamine that can have sedative and calming effects. Some individuals may experience a sense of well-being or euphoria when taking higher amounts, although this is not its intended use and can lead to adverse effects. Misuse of promethazine for recreational purposes is risky and can result in serious health complications. Always use medications as prescribed by a healthcare professional.