Where does the Midwest begin and where does it end?

The Midwest region of the United States generally begins at the western edge of Ohio and extends to the eastern edge of South Dakota and Nebraska. It is typically bounded by the Great Lakes to the north and the Ohio River to the south. The region includes states like Illinois, Indiana, Iowa, Wisconsin, and Michigan, among others. While the exact definition can vary, these geographic markers are commonly used to delineate the Midwest.