Can you take a low dose of cybalta with Effexor?

Combining Cymbalta (duloxetine) and Effexor (venlafaxine) is generally not recommended without close medical supervision, as both medications are serotonin-norepinephrine reuptake inhibitors (SNRIs) and can increase the risk of serotonin syndrome and other side effects. If a healthcare provider deems it necessary, they may prescribe both at low doses, but this should only be done with careful monitoring. Always consult your doctor before making any changes to your medication regimen.