When should you replace spark plugs in a Lexus es 300?

Spark plugs in a Lexus ES 300 should typically be replaced every 60,000 to 100,000 miles, depending on the specific model year and type of spark plugs used. It's important to consult the owner's manual for the manufacturer's recommendations. Additionally, if you notice symptoms like rough idling, difficulty starting, or decreased fuel efficiency, it may indicate that the spark plugs need to be replaced sooner. Regular maintenance checks can help ensure optimal engine performance.