Will a Chevy Express 2500 4l80e fit in a Chevy Express 3500 and does the year matter?

Yes, a Chevy Express 2500 with a 4L80E transmission can generally fit in a Chevy Express 3500, as both models share similar drivetrain components. However, it's important to consider the year, as changes in design and components across model years may affect compatibility. It's advisable to verify specific details for the years in question, as well as to check any additional modifications or adaptations that might be necessary for a proper fit.