Can you take zicam while pregnant?

Like many antibiotics, Azithromycin (the drug in the Z-pack) can cause some unpleasant side effects, including nausea. However, there is no evidence of risk to either the child or mother, including no evidence that azithromycin causes birth defects in either humans or animals. Since azithromycin is a medication you take for only a short period, let your doctor know when he prescribes it and you'll be fine.