To wake a DELL PC from power save mode using a wireless keyboard and mouse, first ensure that the devices are powered on and have working batteries. You can typically press any key on the keyboard or move the mouse to wake the PC. If that doesn't work, try pressing the power button on the PC briefly to see if it exits power save mode. If the issue persists, check the device settings in the BiOS or operating system to ensure that USB wake settings are enabled.
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