How do toads generate poison?

Toads generate poison primarily through specialized glands in their skin, called parotoid glands, which secrete toxic substances known as bufotenin and other bufadienolides. When threatened, toads can excrete these toxins as a defense mechanism to deter predators. The composition and potency of the poison can vary among species, providing varying levels of protection against predation. This adaptation has evolved to enhance their survival in the wild.