Who is spiderman's nemesis?

Spider-Man's primary nemesis is the Green Goblin, also known as Norman Osborn. The character is one of Spider-Man's most iconic villains, known for his intelligence, wealth, and the use of advanced technology combined with a maniacal personality. Their conflict often stems from personal ties, as Osborn's alter ego poses a significant threat to both Peter Parker and those he cares about. Other notable foes include Doctor Octopus, Venom, and the Vulture, but the Green Goblin stands out as a central antagonist in Spider-Man's story.