Can an anaconda kill a tiger?

Yes. An anaconda could kill a tiger if it binded the tiger tightly around its body and suffocated it. In water, the anaconda would kill the tiger as well.

Since the two live on different continents, it would not occur. However, the jaguar, Panthera Onca, is smaller than the tiger, and sometimes kill anacondas. Tigers often kill pythons, by biting the snake's head.