What are proteoglycans and where are they found?

Proteoglycans are large molecules composed of a protein core to which glycosaminoglycan (GAG) chains are attached. They play crucial roles in the extracellular matrix, influencing cell signaling, hydration, and structural integrity of tissues. Proteoglycans are found in various locations throughout the body, including cartilage, skin, and the basement membrane, contributing to the function and resilience of these tissues. Additionally, they are involved in cellular processes such as adhesion, migration, and proliferation.