What causes uremia?

Uremia is primarily caused by the accumulation of waste products in the blood due to impaired kidney function, often resulting from chronic kidney disease, acute kidney injury, or glomerulonephritis. When the kidneys can no longer effectively filter out toxins and excess fluids, these substances build up, leading to symptoms such as fatigue, nausea, and confusion. Other contributing factors may include dehydration, certain medications, and dietary imbalances. Prompt medical intervention is necessary to manage the underlying causes and alleviate symptoms.