What is the half-life of glucocorticoids?

The half-life of glucocorticoids varies depending on the specific compound. For example, cortisol has a half-life of about 60 to 90 minutes, while synthetic glucocorticoids like prednisone and dexamethasone have longer half-lives, typically ranging from several hours to over a day. The half-life can also be influenced by factors such as dosage, route of administration, and individual metabolic differences.