What are the contraindications of morphine sulfate?

Morphine sulfate is contraindicated in patients with severe respiratory depression, acute or severe bronchial Asthma, and known hypersensitivity to the drug. It should also be avoided in individuals with gastrointestinal obstruction, particularly paralytic ileus, and in patients with a history of substance abuse or addiction. Additionally, caution is warranted in those with head injuries or increased intracranial pressure due to its potential to exacerbate these conditions.