What causes hesitation - misfire during acceleration on a corolla -4E -engine?

Hesitation or misfire during acceleration in a Toyota Corolla with a 4E engine can be caused by several factors, including a faulty ignition system (such as worn spark plugs or ignition coils), fuel delivery issues (like a clogged fuel filter or failing fuel pump), or air intake problems (such as a dirty air filter or malfunctioning mass airflow sensor). Additionally, issues with the engine's sensors, such as the oxygen sensor or throttle position sensor, can disrupt the air-fuel mixture, leading to hesitation. Regular maintenance and diagnostics can help identify and resolve these issues.