When and where did the story happen in the last leaf?

"The Last Leaf," a short story by O. Henry, is set in Greenwich Village, New York City, during the early 1900s, particularly in the autumn season. The narrative primarily unfolds in a small, cramped apartment where two young artists, Sue and Johnsy, live and face the challenges of illness and despair. The story's central theme revolves around hope and sacrifice, symbolized by the last leaf clinging to a vine outside their window.