How did the Aztecs civilizations end?

Cortes and his men attacked the Aztec civilization while riding huge horses. The warriors where armed with cross bows and heavy sWords. But not only did Cortes's men wipe out more than half the Aztecs they also brought a killer disease which killed the rest of the Aztecs and ended their civilization for ever.

It is also wise to acknowledge that Cortes did not do this on his own. Along his travel to Tenochtitlan he made allies with other Indian tribes that did not like the Aztecs. This was another key to Cortes' victory over the Aztecs.