Why is there hemoconcentration in eclampsia?

Hemoconcentration in eclampsia occurs due to several factors, primarily related to severe hypertension and increased vascular permeability. In eclampsia, the endothelial dysfunction leads to fluid leakage from the intravascular space into the interstitial tissue, causing a decrease in plasma volume. As a result, the concentration of red blood cells and other solutes increases in the remaining plasma, leading to hemoconcentration. Additionally, the stress response and the activation of the renin-angiotensin-aldosterone system can also contribute to fluid shifts that exacerbate this condition.