Yes and No. . .
The "Yes" part:
They are both Non-Steroidal Anti Inflammatory Drugs (NSAID), but the 81 mg aspirin ("low dose") is typically given to help prevent heart attack and/or stroke. Because 81mg is significantly below the recommended dose for pain relief from aspirin, you can take ibuprofen the same day. However, you want to be careful not to take ibuprofen too often and not to take it in larger than recommended doses. It can cause gastrointestinal problems (stomach ulcers, etc.) and occasionally can cause some liver problems if taken repeatedly and at high doses.
The "No" part:
If a person is taking 81mg aspirin to prevent heart attacks, etc., ibuprofen could potentially lessen the anti-clotting effect of aspirin. It is wise not to take ibuprofen with aspirin if the aspirin is being taken for an anti-coagulation purpose.
Conclusion: You can take ibuprofen with 81mg aspirin, but do not do it often or for an extended amount of time.
*Note: If you took a pain-relief dose of aspirin, such as 325 mg, you would not want to take ibuprofen unless directed to by your practitioner.
ALSO: Make sure to verify with your doctor it is alright to take ibuprofen if you are on other medications. If a person is taking other medications that significantly affect the liver/kidneys or gastrointestinal tract, ibuprofen may not be recommended.
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