When the cross bridge of the myosin molecule forms linkages with actin filaments, it results in muscle contraction. This interaction allows myosin heads to pull the actin filaments toward the center of the sarcomere, shortening the muscle fiber. This process is powered by ATP hydrolysis, which provides the energy necessary for the myosin heads to change conformation and generate force. Ultimately, this cycle of attachment, pivoting, and detachment leads to the sliding filament mechanism of muscle contraction.
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